| 1 | Claudia Lane | 2019 | Malibu High School (SS) | 16:30.30 | -- | |
| 2 | Haley Herberg | 2018 | Capistrano Valley High (SS) | 17:00.00 | 1 | |
| 3 | Mariah Castillo | 2018 | Saugus High School (SS) | 17:15.70 | 2 | |
| 4 | Corie Smith | 2020 | Buchanan High School (CS) | 17:16.70 | 3 | |
| 5 | Meagen Lowe | 2019 | Buchanan High School (CS) | 17:19.80 | 4 | |
| 6 | Elena Denner | 2018 | Oak Ridge High School (SJ) | 17:27.60 | 5 | |
| 7 | Fatima Cortes | 2019 | Great Oak High School (SS) | 17:32.10 | 6 | |
| 8 | Lauren Peurifoy | 2019 | King (Martin Luther Jr.) (SS) | 17:32.50 | 7 | |
| 9 | Sara Leonard | 2018 | Canyon Anaheim Hills (SS) | 17:34.60 | 8 | |
| 10 | Tori Gaitan | 2020 | Great Oak High School (SS) | 17:35.90 | 9 | |
| 11 | Emily Virtue | 2018 | Burroughs Burbank (SS) | 17:36.10 | -- | |
| 12 | Chloe Arriaga | 2019 | Walnut High (SS) | 17:40.90 | -- | |
| 13 | Alyssa Bautista | 2018 | Capistrano Valley High (SS) | 17:45.60 | 10 | |
| 14 | Gillian Wagner | 2018 | Redwood High School (NC) | 17:49.30 | -- | |
| 15 | Mari Friedman | 2018 | Santa Cruz High (CC) | 17:49.60 | 11 | |
| 16 | Alize Hartke | 2018 | Oakmont High (SJ) | 17:54.30 | -- | |
| 17 | Sandra Pflughoft | 2018 | Great Oak High School (SS) | 17:55.70 | 12 | |
| 18 | Caroline Garrett | 2019 | Oakland Technical Senior High (OK) | 17:57.20 | 13 | |
| 19 | Olivia O'keeffe | 2018 | Davis Senior High School (SJ) | 17:59.20 | 14 | |
| 20 | Misty Diaz | 2018 | Norwalk High (SS) | 18:01.40 | -- | |
| 21 | Mckenna Brown | 2018 | La Costa Canyon (SD) | 18:02.50 | 15 | |
| 22 | Paige Haynes | 2019 | Vista Murrieta (SS) | 18:04.00 | 16 | |
| 23 | Audrey Suarez | 2021 | Mayfield (G) (SS) | 18:04.10 | 17 | |
| 24 | Kelli Hines | 2019 | Mission Viejo High School (SS) | 18:04.80 | 18 | |
| 25 | Colleen Mccandless | 2019 | Granada High (NC) | 18:06.10 | 19 |